“This collaborative project between the National Library of Medicine (NLM) and Folger Shakespeare Library blends the history of medicine with the insightful literature of Shakespeare. The project integrates the historically popular but now discredited medical theory that bodily fluids–blood, yellow bile, black bile, and phlegm–were the basis for personality traits and behavior and were reflected in literature. Using this Hippocratic theory, Shakespeare’s characters are analyzed through a humorist lens. The physical exhibit was on view at the NLM from January to August 2012. The electronic exhibit consists of images (paintings, imprints, and so on) of primary sources from the NLM and Folger collections. An explanation of the humors is provided and is used to analyze protagonists in Taming of the Shrew (Kate and Petruchio), Hamlet (Ophelia), and Merchant of Venice (Shylock). — J. P. Kilham, University of Connecticut Health Center